stem cells in their environment

team >

emanuel rognoni

nationality

German Italian

role

Postdoc

qualifications

•  PhD (Dr. rer. nat.), Max-Planck-Institute of Biochemistry, Germany, 2014

•  MSc in Biochemistry, TU-Munich, Germany, 2008

•  BSc in Biochemistry, TU-Munich, Germany, 2008

research project title

'Analysis of dermal fibroblast subpopulations in tumors in response to aberrant epidermal Wnt-signaling'

core expertise

•  Integrin signaling

•  Cancer mouse models

•  Immunohistochemistry

•  Histology

•  Confocal microscopy

•  Flow cytometry

•  Molecular biology and cell biology techniques

•  Oncolytic adenoviruses

blog

•  Extracellular Matrix: New Perspectives for Translational Medicine, Freiburg - 15 March 2016

publications

[Full PubMed list]

•  ‘Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties’ Donati G, Rognoni E, Hiratsuka T, Liakath-Ali K, Hoste E, Kar G, Kayikci M, Russell R, Kretzschmar K, Mulder KW, Teichmann SA, Watt FM. Nat Cell Biol. 2017 May 15. doi: 10.1038/ncb3532. PMID: 28504705 [PubMed] [SharedIT link]

•  ‘A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.’ Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM. Nat Commun. 2017 Mar 23;8:14744. doi: 10.1038/ncomms14744. PMID: 28332498 [PubMed]

•  Rognoni E, Gomez C, Pisco AO, Rawlins EL, Simons BD, Watt FM, Driskell RR. 'Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.' Development. 2016 Jun 10. pii: dev.131797. PMID: 27287810 [PubMed]

•  Kaushal GS, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM. 'Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation.' J Invest Dermatol. 2015 Aug 19. doi: 10.1038/jid.2015.319. [Epub ahead of print] PMID: 26288357 [PubMed]

•  'Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation.' Rognoni E, Widmaier M, Jakobson M, Ruppert R, Ussar S, Katsougkri D, Böttcher RT, Lai-Cheong JE, Rifkin DB, McGrath JA, Fässler R. Nat Med. 2014; 20(4), 350-9. PMID: 24681597 [PubMed]

•  'Visualization of endothelial actin cytoskeleton in the mouse retina.' Fraccaroli A, Franco CA, Rognoni E, Neto F, Rehberg M, Aszodi A, Wedlich-Söldner R, Pohl U, Gerhardt H, Montanez E. PLoS One. 2012; 7(10): e47488. PMID: 23115648 [PubMed]

•  'Integrin-linked kinase at a glance.' Widmaier M, Rognoni E, Radovanac K, Azimifar SB, Fässler R. J Cell Sci. 2012; 125(Pt 8), 1839-1843. PMID: 22637643 [PubMed]

•  'Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction.' Ussar S, Moser M, Widmaier M, Rognoni E, Harrer C, Genzel-Boroviczeny O, Fässler R. PLoS Genet. 2008; 4(12): e1000289. PMID: 19057668 [PubMed]

•  'YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.' Holzmüller R, Mantwill K, Haczek C, Rognoni E, Anton M, Kasajima A, Weichert W, Treue D, Lage H, Schuster T, Schlegel J, Gänsbacher B, Holm PS. Int J Cancer. 2011; 129(5), 1265-1276. PMID: 21710499 [PubMed]

•  'Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo.' Rognoni E, Widmaier M, Haczek C, Mantwill K, Holzmüller R, Gansbacher B, Kolk A, Schuster T, Schmid RM, Saur D, Kaszubiak A, Lage H,  Holm PS. Cancer Gene Ther. 2009; 16(10), 753-763. PMID: 19363467 [PubMed]