stem cells in their environment

team >

fiona watt

nationality

British

role

Director - Centre for Stem Cells and Regenerative Medicine,
King's College London

qualifications

•  DPhil University of Oxford, 1979

•  BA Hons, Natural Sciences, University of Cambridge, 1976

research project title

'Intrinsic and extrinsic control of stem cell fate'

core expertise

Cell biology

publications

[Full PubMed list]

•  ‘Seven actionable strategies for advancing women in science, engineering, and medicine.’ Smith KA, Arlotta P, Watt FM; Initiative on Women in Science and Engineering Working Group, Solomon SL. Cell Stem Cell. 2015 Mar 5;16(3):221-4. doi: 10.1016/j.stem.2015.02.012. PMID: 25748929 [PubMed]

•  ‘Innate sensing of microbial products promotes wound-induced skin cancer.’ Hoste E, Arwert EN, Lal R, South AP, Salas-Alanis JC, Murrell DF, Donati G, Watt FM. Nat Commun. 2015 Jan 9;6:5932. doi: 10.1038/ncomms6932. PMID: 25575023 [PubMed]

•  ‘Understanding fibroblast heterogeneity in the skin.’ Driskell RR, Watt FM. Trends Cell Biol. 2015 Feb;25(2):92-99. doi: 10.1016/j.tcb.2014.10.001. Epub 2014 Nov 7. PMID: 25455110 [PubMed]

•  ‘Mammalian skin cell biology: at the interface between laboratory and clinic.’ Watt FM. Science. 2014 Nov 21;346(6212):937-40. doi: 10.1126/science.1253734.PMID: 25414300 [PubMed]

•  ‘BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions.’ Kretzschmar K, Cottle DL, Donati G, Chiang MF, Quist SR, Gollnick HP, Natsuga K, Lin KI, Watt FM. Stem Cell Reports. 2014 Oct 14;3(4):620-33. doi: 10.1016/j.stemcr.2014.08.007. Epub 2014 Sep 18. PMID: 25358790 [PubMed]

•  ‘Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.’ DiTommaso T, Jones LK, Cottle DL; WTSI Mouse Genetics Program, Gerdin AK, Vancollie VE, Watt FM, Ramirez-Solis R, Bradley A, Steel KP, Sundberg JP, White JK, Smyth IM. PLoS Genet. 2014 Oct 23;10(10):e1004705. doi: 10.1371/journal.pgen.1004705. eCollection 2014 Oct. PMID: 25340873 [PubMed]

•  Benaich N, Woodhouse S, Goldie SJ, Mishra A, Quist SR, Watt FM. ‘Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.’ Cell Rep. 2014 Oct 9;9(1):104-17. doi: 10.1016/j.celrep.2014.08.062. Epub 2014 Oct 2. PMID: 25284788 [PubMed]

•  ‘Advancing research.’ Patterson M, Schekman R, Watt FM, Weigel D. Elife. 2014 Aug 13;3:e03980. doi: 10.7554/eLife.03980. PMID: 25122625 [PubMed]

•  ‘Modulating the stem cell niche for tissue regeneration.’ Lane SW, Williams DA, Watt FM. Nat Biotechnol. 2014 Aug 5. doi: 10.1038/nbt.2978. [Epub ahead of print] PMID: 25093887 [PubMed]

•  ‘Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin.’ Kretzschmar K, Watt FM. Cold Spring Harb Perspect Med. 2014 Jul 3. pii: a013631. doi: 10.1101/cshperspect.a013631. [Epub ahead of print] PMID: 24993676 [PubMed]

•  ‘Defining dermal adipose tissue.’ Driskell R, Jahoda CA, Chuong CM, Watt F, Horsley V. Exp Dermatol. 2014 May 19. doi: 10.1111/exd.12450. [Epub ahead of print] PMID: 24993676 [PubMed]

•  ‘Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.’ Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1501-9. doi: 10.1073/pnas.1312880111. Epub 2014 Mar 31. PMID: 24706781 [PubMed]

•  ‘Distinct fibroblast lineages determine dermal architecture in skin development and repair.’ Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM. Nature. 2013 Dec 12;504(7479):277-81. doi: 10.1038/nature12783. PMID: 24336287 [PubMed]

•  'The basement membrane of hair follicle stem cells is a muscle cell niche.' Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM. Cell. 2011 Feb 18;144(4):577-89. doi: 10.1016/j.cell.2011.01.014. PMID: 21335239 [PubMed]

•  'Diverse epigenetic strategies interact to control epidermal differentiation.' Mulder KW, Wang X, Escriu C, Ito Y, Schwarz RF, Gillis J, Sirokmány G, Donati G, Uribe-Lewis S, Pavlidis P, Murrell A, Markowetz F, Watt FM. Nat Cell Biol. 2012 Jun 24;14(7):753-63. doi: 10.1038/ncb2520. PMID: 22729083 [PubMed]

•  'Extracellular-matrix tethering regulates stem-cell fate.' Trappmann B, Gautrot JE, Connelly JT, Strange DG, Li Y, Oyen ML, Cohen Stuart MA, Boehm H, Li B, Vogel V, Spatz JP, Watt FM, Huck WT. Nat Mater. 2012 May 27;11(7):642-9. doi: 10.1038/nmat3339. Erratum in: Nat Mater. 2012 Aug;11(8):742. PMID: 22635042 [PubMed]