stem cells in their environment

team >

toru hiratsuka

nationality

Japanese

role

PostDoc

qualifications

•  MD, Osaka University, Japan, 2011

•  PhD (medicine), Kyoto University, Japan, 2015

research project title

'MAPK activity visualization in human keratinocytes and mouse skin.'

core expertise

•  Two photon excitation microscopy

•  FRET biosensor

•  Mouse models

publications

[Full PubMed list]

Note: Since some names are more common than others, search may need more refining to specifically target this researcher.

•  ‘Propagating Wave of ERK Activation Orients Collective Cell Migration’ Kazuhiro Aoki, Yohei Kondo, Honda Naoki, Toru Hiratsuka, Reina E Itoh, Michiyuki Matsuda. Dev Cell. 2017 Nov 6. doi: 10.1016/j.devcell.2017.10.016 PMID: 29112851 [PubMed]

•  ‘Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle.’ Sakaue-Sawano A, Yo M, Komatsu N, Hiratsuka T, Kogure T, Hoshida T, Goshima N, Matsuda M, Miyoshi H, Miyawaki A. Mol Cell. 2017 Oct 25 doi: 10.1016/j.molcel.2017.10.001. PMID: 29107535 [PubMed]

•  ‘Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties’ Donati G, Rognoni E, Hiratsuka T, Liakath-Ali K, Hoste E, Kar G, Kayikci M, Russell R, Kretzschmar K, Mulder KW, Teichmann SA, Watt FM. Nat Cell Biol. 2017 May 15. doi: 10.1038/ncb3532. PMID: 28504705 [PubMed] [SharedIT link]

•  'Physiological ER stress mediates the differentiation of fibroblasts.' Matsuzaki S*, Hiratsuka T*, Taniguchi M, Shingaki K, Kubo T, Kiya K, Fujiwara T, Kanazawa S, Kanematsu R, Maeda T, Takamura H, Yamada K, Miyoshi K, Hosokawa K, Tohyama M, Katayama T (* co-first authors). PLoS One. 2015;10(4):e0123578. Epub 2015 Apr 30. PMID: 25928708 [PubMed]

•  'Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.' Hiratsuka T, Fujita Y, Naoki H, Aoki K, Kamioka Y, Matsuda M. Elife. 2015;4: e05178. Epub 2015 Feb 10. PMID: 25668746 [PubMed]

•  'Yokukansan inhibits neuronal death during ER stress by regulating the unfolded protein response.' Hiratsuka T*, Matsuzaki S*, Miyata S, Kinoshita M, Kakehi K, Nishida S, Katayama T, Tohyama M (* co-first authors). PLoS One. 2010;5(10): e13280, 2010 Oct 12. PMID: 20967273 [PubMed]

•  'Familial amyotrophic lateral sclerosis (FALS)-linked SOD1 mutation accelerates neuronal cell death by activating cleavage of caspase-4 under ER stress in an in vitro model of FALS.' Koyama Y*, Hiratsuka T*, Matsuzaki S*, Yamagishi S, Kato S, Katayama T, Tohyama M (* co-first authors). Neurochem. Int. 2010;57(7): p.838–843, Epub 2010 Sep 21. PMID: 20816908 [PubMed]

•  'Caspase-4 is partially cleaved by calpain via the impairment of Ca2+ homeostasis under the ER stress.' Matsuzaki S*, Hiratsuka T*, Kuwahara R*, Katayama T, Tohyama M (* co-first authors). Neurochem. Int. 2010;56(2): p.352–356, Epub 2009 Nov 17. PMID: 19931333 [PubMed]